Please, find attached to this email a new
study, "Neurodevelopmental Disorders Following
Thimerosal-Containing Childhood Immunizations:
A Follow-up Analysis"
[See:
NeuroDevelopmental Disorders Following TCVs -
A Follow-up Analysis
[Adobe Acrobat Format,
177 K]] just published in the
peer-reviewed scientific/medical International
Journal of Toxicology (American College of
Toxicology). The authors previously published
the first epidemiological study from the
United States associating thimerosal from
childhood vaccines with neurodevelopmental
disorders based upon assessment of the Vaccine
Adverse Event Reporting System (VAERS)
database. A number of years have gone by since
their previous analysis of the VAERS. The
present completely open epidemiological study
was undertaken to determine whether the
previously observed effect between thimerosal
containing childhood vaccines and
neurodevelopmental disorders rare still
apparent in the VAERS as children have had a
chance to further mature and be diagnosed with
additional neurodevelopmental disorders. In
the present study, a cohort of children
receiving thimerosal-containing
Diphtheria-Tetanus-acellular-Pertussis (DTaP)
vaccines in comparison to a
cohort of children receiving thimerosal-free
DTaP vaccines administered from 1997 through
2000 based upon an assessment of adverse
events reported to the VAERS database (online
VAERS database updated through 28 February
2004) were evaluated.
It was determined that there were
significantly increased odds ratios (ORs) for
autism
(OR = 1.8 p < 0.05), mental retardation (OR =
2.6, p < 0.002), speech disorders
(OR = 2.1, p < 0.02), personality disorders
(OR = 2.6, p < 0.01), and thinking
abnormalities (OR = 8.2, p < 0.01) reported to
the VAERS database following thimerosal-containing
DTaP vaccines in comparison to thimerosal-free
DTaP vaccines. Potential confounders and
reporting biases were found to be minimal in
this assessment of the VAERS. It was observed,
even though the media has reported a potential
association between autism and thimerosal
exposure, that the other neurodevelopmental
disorders analyzed in this assessment of the
VAERS database had significantly higher odds
ratios than autism following thimerosal-containing
DTaP vaccines in comparison to thimerosal-free
DTaP vaccines.
The present study provides additional
epidemiological evidence supporting previous
epidemiological, clinical and experimental
evidence that administration of thimerosal-containing
vaccines in the United States resulted in a
significant number of children developing
neurodevelopmental disorders. The authors
concluded, "Despite, the recent conclusion
from the National Academy of Sciences'
Institute of Medicine that there is no
evidence of relationship between thimerosal
and autism, and that no further scientific
research should be undertaken to evaluate to
evaluate the relationship between thimerosal
and autism, the results of the present study,
taken with data recently published by a number
of researchers,
demonstrate a connection between mercury
exposure via infant vaccinations and the
dramatic increase in autism and other
neurodevelopmental disorders in the United
States. It is clear that the results of the
present study, mandate that additional
research should be undertaken, no only for
autism, but other childhood neurodevelopmental
disorders, by evaluating childhood
mercury-associated exposures, especially from
thimerosal-containing childhood vaccines."
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